Evaluation of iron overload: dual-energy computed tomography versus magnetic resonance imaging
نویسندگان
چکیده
Background Iron toxicity is key factor for tissue damage in ironoverloaded patients, with induced heart failure as the main cause of death. T2*-weighted MRI has been established as the method of choice for evaluating iron-content with strong correlation with biopsy, where T2* < 20 ms and T2* < 10 ms at 1.5T indicate iron overload and severe iron overload, respectively. Recently-introduced dualenergy CT (DECT) has the potential for evaluating iron overload without energy-dependent CT attenuation or tissue fat effects. The aim of this study is to investigate the performance of DECT for iron mapping in in-vitro scans of calibrated iron phantoms and compare results to MRI.
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